Stat 1 tyrosine phosphorylation (research and development assay)

Stat 1 tyrosine phosphorylation

Immunology

For patients with recurrent viral infections, IFN-α may be used to assess tyrosine phosphorylation of STAT 1. For patients with chronic mucocutaneous candidiasis increased tyrosine phosphorylation of STAT 1 may indicate a gain of function STAT 1 mutation

2mls EDTA plus a healthy control sample. Please send 1ml extra EDTA for DNA storage

Samples should be less than 24 hours old. R&D Assay. This test should only be undertaken under the direction of a Consultant Immunologist/ Senior Clinical Scientist. External referrals must be discussed with Dr Kimberly Gilmour (020 7813 8466) or her deputy and accompanied by a completed referral form (available on website)

5 days

Not applicable

No (research)