https://www.gosh.nhs.uk/wards-and-departments/departments/laboratory-medicine/laboratory-database/immunohistochemistry/
Immunohistochemistry
EPIC
Various
Section
Histopathology
Description
Technical stain only (no histopathologist interpretation). Detection of the following antigens:
ACTH, Adenovirus, (Pan-cytokeratin) AE1/AE3, ALK-1, Alzheimer precursor protein (APP), Alpha Feto-protein (AFP), ATRX, Beta-catenin (β-catenin), BCL2, BCL6, BCOR, (Ep-Cam) Ber-EP4, Bombesin, Brachyury, BRAF*, C4d, Calcitonin, Calretinin, CD1a, CD2, CD3, CD4, CD5, CD8, CD10, CD14, CD15, CD19, CD20, CD21, CD25, CD30, CD31, CD34, CD45, CD56, CD61, CD68 (KP1), CD68 (PG-M1), CD79a, CD909, CD117 (c-kit), CD138, CD163, CEA (Carcino Embryonic Antigen), Chromogranin A, CMV, (Cytomegalovirus), Cyclin D1, Cytokeratin 7 (CK7), Cytokeratin 14 (CK14), Cytokeratin 19 (CK19), Cytokeratin 20 (CK20), (Podoplanin) D2-40, Desmin, EMA, ERG, EZHIP (CXorf67), Factor 8, Factor 13a, Fascin, FOXP3, FSH, GAB1, GFAP, Glucagon, Glut-1, Glycophorin C, Glypican-3, H. Pylori, H3G34R, H3K27M, H3K27me3, HCG, Human Growth Hormone, HLA-DR, HMB45 (Melanosome), HSV 1, HSV 2, IDH1, Inhibin, INI-1 (BAF47, SMARCB1), INSM1*, Insulin, IgG4, Ki-67, L1CAM, Langerin, LIN28a, Luteinizing hormone, Lysozyme, MAP2, Mast Cell Tryptase (MCT), Melan-A*, (MMR) MLH1, (MMR) MSH2, (MMR) MSH6, (MMR) PMS2, (Pan-cytokeratin) MNF116, MUM-1, Myeloperoxidase (MPO, MPX), MyoD1*, Myogenin, NeuN, Neurofilament 66 kD, Neurofilament 200 kD, NSE, NUT1*, OCT 3/4, OLIG2, P4EBP, P53, p62*, P65 (RELA), PAX5, Pancreatic cocktail, pan-NTRK*, Pancreatic polypeptide, Parvovirus, PIT-1, PHOX2B, PLAP, Proinsulin, Prolactin, PS6, RT97, S100, SALL4, Sars-cov-2, SF-1, SMA (Smooth Muscle Actin), SMARCA4 (BRG1), Somatostatin, SOX10*, Surfactant B, SV40, Synaptophysin, TCR delta gamma, TdT, TFE3, TLE-1, T-PIT, Toxoplasma, Transthyretin (TTR, Prealbumin), TSH, TTF-1, Vimentin, WT1, YAP, Znt3*
Specimen requirement
Unstained adhesive slides or FFPE block. 2-3μm thickness sections
Dispatch and handling instructions
Padded envelope. Glass slides is mailers. FFPE blocks appropriately secured. Room temperature
Turnaround time
48 hours
Synonym
IHC, ICC
Is it IS0 15189 Accredited?
Yes
BRAF*, CRX*, INSM1*, Melan-A*, MyoD1*, p62*, pan-NTRK*, NUT1*, SOX10*, TCR delta gamma*, Znt3*
*Pending UKAS accreditation