Extractable nuclear antigens

EPIC

ANA/dsDNA/ENA

Section

Immunology

Clinical indications

If ANA positive ENA screen will be done: Includes Ro, La, Sm, RNP, Jo-1, Scl-70, centromere. If screen positive, sample will be sent to Royal London for typing. Not quantitative. ENAs may evolve during the course of paediatric connective tissue disease

Specimen requirement

ANA sample serum /serum gel. Serological assays may be affected by icteric/lipaemic/haemolysed samples. These should be avoided if possible

Dispatch and handling instructions

In house/ sent to Royal London

Turnaround time

Screen: 8 days

Type: 28 days

Synonym

Not applicable

Is it IS0 15189 accredited?

Yes