Bone marrow or peripheral blood stem cell manipulations: TCR α/β depletion

EPIC

TCR α/β depletion

Section

Immunology

Clinical indications

Manipulation of bone marrow or PBSCs may be required to deplete T and B cells (alpha/beta and CD19 depletion)

Specimen requirement

HPC (M) or HPC (A) with up to 60 x 10^9 total cells or 24 x 10^6 TCRαβ cells

Dispatch and handling instructions

All manipulations can only be performed if booked well in advance (at least 1 week) with the CTL on ext on 0433/0205 and an approved protocol is provided

Turnaround time

3 days

Synonym

Not applicable

Is it IS0 15189 accredited?

Yes: Staining – Post TCRαβ/CD19 Depletion. Monitoring Post Cell Manipulations: CD34 and CD3 Enumeration and viability