https://www.gosh.nhs.uk/wards-and-departments/departments/laboratory-medicine/laboratory-database/arylsulphatase-b/

Arylsulphatase B

EPIC

MPS VI

Section

Chemical Pathology - Enzyme

Clinical indications

For the diagnosis of MPS Type VI. Arylsulphatase B is deficient in leucocytes and cultured cells in cases of Mucopolysaccharidosis Type VI (Maroteaux-Lamy syndrome)

Specimen requirement

1. 5 - 10 mL lithium heparin whole blood or

2. Cultured fibroblasts or

3. Chorionic villi or

4. Cultured chorionic villi or

5. Cultured amniotic cells

Dispatch and handling instructions

1. Send whole blood at ambient room temperature to reach the lab ideally within 24 hours of collection

2. Send flask completely filled with medium at room temperature a in well insulated container. To reach lab ideally within 24 hours

3. Contact the Enzyme Laboratory PRIOR to sampling and shipping

4. Contact the Enzyme Laboratory PRIOR to sampling and shipping

5. Contact the Enzyme Laboratory PRIOR to sampling and shipping

Turnaround time

1. 4 to 6 weeks

2. 4 to 6 weeks

3. As soon as practically possible

4. As soon as practically possible

5. As soon as practically possible

Synonym

Mucopolysaccharidosis Type VI, MPS6, Maroteaux-Lamy syndrome, N-Acetylgalactosamine-4-sulphatase

Is it IS0 15189 accredited?

1. Yes

2. Yes

3. Yes

4. Yes

5. Yes