Apoptosis functional

EPIC

Apoptosis functional

Section

Immunology

Clinical indications

Screening assay for defects in the apoptosis pathway (including Fas, FASL, caspase 8 and caspase 10). Defects in this pathway are associated with ALPS

Specimen requirement

5 mls lithium heparin plus a healthy control sample. Please send 1ml extra EDTA for DNA storage

Dispatch and handling instructions

Samples should be less than 24 hours old. Requested after discussion with Clinical Lead, laboratory manager or senior healthcare scientist. Reason for request must be stated. This test should only be undertaken under the direction of a Consultant Immunologist/ Senior Clinical Scientist. External referrals must be discussed with Dr Kimberly Gilmour (020 7813 8466) or her deputy and accompanied by a completed referral form (available on website)

Turnaround time

30 days

Synonym

Not applicable

Is it IS0 15189 accredited?

Yes