Conditions treated by the Cloacal Malformation Multidisciplinary Service team

Information about the conditions treated as part of the Cloacal Malformation Multidisciplinary Service at Great Ormond Street Hospital. 
 Cloacal malformation is a congenital problem which occurs in 1 in 50,000 births and is exclusively seen in females. During development, the urethra, vagina and anus fail to separate resulting in a common channel which opens onto the perineum. There are associated malformations in more than 90% of cases. Around 60% of girls with cloacal malformations have kidney problems, 50% have renal failure at 5 years of age and up to 20% need renal replacement therapy, such as dialysis or transplant, before transition to young adult services.