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Neuromyelitis optica spectrum disorder

Neuromyelitis optica spectrum disorder (NMOSD) is a rare neurological (brain) condition characterised by episodes of optic neuritis (inflammation or swelling of the optic nerve), transverse myelitis (inflammation or swelling of the spinal cord), together

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Neurophysiology monitoring during surgery

This page from Great Ormond Street Hospital (GOSH) explains the procedure for spinal cord monitoring during surgery.

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Sajid Javid on PICU ward

Secretary of State for Health and Social Care visits GOSH

30 Mar 2022, 1:40 p.m.

On Tuesday 29 March, Rt Hon Sajid Javid MP Secretary of State for Health and Social Care, visited our hospital to host a roundtable discussion on rare diseases.

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ICH researchers develop a technique to 'print' healthy new tissue

24 Jun 2020, 12:51 p.m.

A pioneering international study led by the UCL Great Ormond Street Institute of Child Health (ICH) has seen researchers develop a photosensitive bio-gel that uses light treatment to ‘print’ healthy new tissue directly into specific tissues and organs, an

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Adult helping a child in goggles with a pipette

Raising awareness on Rare Disease Day

8 Mar 2024, 12:04 p.m.

To celebrate Rare Disease Day we invited patients and their families to try out 13 different hands-on and interactive fun and educational science and research activities for children and adults.

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Clinical services at the Dubowitz Neuromuscular Centre

The Dubowitz Neuromuscular Centre provides a comprehensive multidisciplinary assessment, diagnostic and management service for children with neuromuscular disorders.

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Positive interim analysis of Phase 3 studies in spinal muscular atrophy

14 Dec 2016, 10:02 a.m.

Biogen and Ionis Pharmaceuticals announce positive results at interim analysis of two Phase 3 studies both trialling the drug nusinersen in patients with spinal muscular atrophy (SMA).

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Nursing_Ortho

Caring for Children and Young People with Orthopaedic or Spinal Conditions

This module provides practitioners with an opportunity to develop their knowledge, skills and competence in caring for children and young people with an orthopaedic or spinal condition.

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Intrathecal methotrexate

Methotrexate is a chemotherapy drug that is used to treat certain types of cancer and leukaemia. When given intrathecally, it prevents leukaemia cells entering the cerebrospinal fluid (CSF) around the spine and brain. It is also used to treat leukaemia fo

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Exploring scoliosis with Mark Harris

12 Sep 2019, 11:22 a.m.

During Paul O’Grady’s Little Heroes series two, we’re shining a spotlight on the inspiring staff across the hospital who help children get better and fulfil their potential. Consultant spinal surgeon Mark Harris treated patient Reagan, who features on epi

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MOG antibody demyelination

This information from Great Ormond Street Hospital (GOSH) explains about Myelin Oligodendrocyte Glycoprotein (MOG) antibodies and the symptoms and treatment of MOG antibody associated demyelination.

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About the Limb Reconstruction Unit

The Limb Reconstruction Unit forms part of the Orthopaedic and Spine Surgery department at Great Ormond Street Hospital (GOSH). It is a tertiary referral service specialising in unusual or difficult cases of upper and/or lower limb deformity or length dif

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Clinics and wards related to the Neuroimmunology Centre

The Neuroimmunology centre is both outpatient and inpatient based depending on your child's condition and the treatment they are on.

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Bowel washouts using an antegrade colonic enema (ACE)

Bowel washouts are a method of dealing with constipation or with soiling, which is the leakage of faeces (poo) other than during a bowel movement. If other methods fail, doctors may recommend bowel washouts using an antegrade colonic enema (ACE). This can

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Acute flaccid myelitis

Acute flaccid myelitis (AFM) is a rare condition that tends to occur in ‘outbreaks’ every few years. It affects the spinal cord – particularly the grey matter – and over hours to days muscles weaken and normal limb reflexes disappear. It often follows a m

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Spinraza: the first treatment for spinal muscular atrophy to receive FDA approval

30 Mar 2017, 11:28 a.m.

At the end of 2016, the American Food and Drug Administration (FDA) granted approval for the use of Spinraza (nusinsersen) for the treatment of spinal muscular atrophy (SMA) in paediatric and adult patients. This is unprecedented for the SMA community wit

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Catheterisation using a Mitrofanoff

This page explains about cathererisation using a Mitrofanoff and what to expect when your child comes to Great Ormond Street Hospital (GOSH) to have this procedure.

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Conditions treated at the Dubowitz Neuroluscular Centre

The Dubowitz Neuromuscular Centre (DNC) treats a wide range of neuromuscular disorders in children.

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A network of blue and purple branching tubes on a black background. The image shows many layers providing a 3D effect. There are yellow dots throughout around the image.

Stunning images showcase life-changing research at GOSH

28 Feb 2023, 9 a.m.

A captivating 3D image that is helping researchers to uncover the secrets of childhood cancers is crowned the winner of our 2022/23 image competition ‘A moment of discovery’.

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Research in lab

NIHR GOSH BRC Translational Research (Non-Clinical) PhD Studentships

CLOSED: GOSH BRC Studentship Programme aims to fund five highly motivated non-clinical PhDs students to support the training and development of the next generation of translational researchers.

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