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Marking Rare Disease Day 2023

7 Mar 2023, 11 a.m.

Rare Disease Day is a global event that aims to raise awareness and generate change for those living with rare diseases. At GOSH, many of our patients and families are part of the rare disease community and so this year we were delighted to mark the…

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New commercial agreement for gene therapy at GOSH

16 Mar 2023, 9:57 a.m.

Great Ormond Street Hospital for Children (GOSH) and Leucid Bio have entered a new commercial agreement to manufacture a gene therapy product.

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Adeno-associated viruses implicated in disease in world-first

30 Mar 2023, 4 p.m.

A research team spanning GOSH and UCL has, for the first time, connected adeno-associated viruses with development of hepatitis in some children

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A return of the NIHR GOSH BRC academic training weekend

25 Apr 2023, 9 a.m.

The weekend is part of a programme of training opportunities that the NIHR GOSH BRC offers to the wider paediatric research community and aimed to support attendees as they transition to independent researchers.

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GOSH and Roche UK partnership using AI to bring personalised healthcare to children

16 May 2023, 10 a.m.

GOSH and Roche UK have partnered to harness the power of data by co-develop digital tools. This can uncover better ways to care for children and young people with rare and complex diseases.

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GOSH staff recognised in prestigious research prize

18 May 2023, noon

Four members of staff from GOSH and UCL GOS ICH have today been recognised by the Academy of Medical Sciences for their exceptional contributions to the advancement of biomedical and health science

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Transitioning clinical trials at GOSH

20 May 2023, 7 a.m.

At GOSH we run hundreds of clinical trials each year, many of which take place in our dedicated facility - the NIHR GOSH CRF. But how do we transition trials out of the facility into a new setting?

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How 3D ‘bio-printing’ can shape mini-organs

9 Jun 2023, 4 p.m.

Scientists have shown for the first time how 3D printing can be achieved inside ‘mini-organs’ growing in hydrogels - controlling their shape, activity, and even forcing tissue to grow into ‘moulds’.

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Celebrating International Clinical Trials Day with our patients and families

21 Jun 2023, 11 a.m.

On 19 May we enjoyed welcoming patients, their families and GOSH staff, including GOSH nursery to the Lagoon to celebrate International Clinical Trials Day as well as the NIHR “Be Part of Research" campaign.

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GOSH receives over £3.5m for research and innovation

28 Jun 2023, 11:31 a.m.

GOSH has been awarded over £3.5m by the NIHR for vital research and innovation equipment that will help to improve treatments for children

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Unlocking the mystery of long-lasting cancer treatment

6 Jul 2023, 8 a.m.

Researchers from across GOSH, UCL GOS ICH and the Wellcome Sanger Institute have published new insights that explain why some children have a longer remission than others after having cutting-edge CAR T-cell therapy for leukaemia.

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Global genomic collaboration improves lives and treatment for children with epilepsy

17 Aug 2023, 8 a.m.

An international research collaboration, including GOSH and our research partner UCL Institute of Child Health, has shown that a technique known as rapid genome sequencing can provide a diagnosis for 43 per cent of children with unexplained epilepsy.

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Steps forward in gene therapy for hearing loss linked to rare disease

29 Aug 2023, 3 p.m.

An international team led by researchers at GOSH, UCL and the NIHR GOSH BRC have developed in mice a gene therapy that significantly reduces the hearing loss associated with Norrie disease.

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Over 300 innovative projects completed since the launch of GOSH DRIVE in 2018

25 Sep 2023, 1:09 p.m.

The Data Research, Innovation and Virtual Environments (DRIVE) unit at GOSH was launched five years ago. Our new report explains how this first-of-its-kind unit has led to improvements in research and innovation, and care for children and young people.

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A showcase of research

7 Sep 2023, 5:12 p.m.

This summer saw the return of the NIHR GOSH BRC showcase.

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GOSH patient first in the UK to receive improved kidney transplant

22 Sep 2023, 10 a.m.

Eight-year-old Aditi is the first child in the UK and on the NHS to be taken off immunosuppressants just one-month after kidney transplant at Great Ormond Street Hospital (GOSH).

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GOSH receives new MHRA authorisation to manufacture viral vectors

1 Nov 2023, 5 p.m.

GOSH has been granted a Manufacturer's Authorisation Licence for the manufacture of viral vectors, which will accelerate Cell and gene therapies (CGT) clinical trials worldwide and expand the novel treatments that we can offer to our patients.

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Clinical trial results give new hope for children with rare brain tumours

18 Nov 2023, 8 a.m.

Researchers who are searching for better treatments for an incredibly rare type of brain tumour have published successful results from the latest rounds of clinical trials.

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GOSH to provide support for AI and Machine Learning as part of new paediatric HealthTech Research Centre

23 Nov 2023, 10 a.m.

GOSH will support the new Child and Young People’s HealthTech Research Centre (HRC), led by Sheffield Children’s Hospital, as leads for AI and Machine Learning.

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Reducing oxygen levels for children in intensive care will save lives

1 Dec 2023, 11:30 p.m.

A new landmark study led from GOSH has found that reducing oxygen levels for critically ill children on mechanical ventilators in intensive care could save lives

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