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New director of UCL Great Ormond Street Institute of Child Health

30 Jun 2022, 5 p.m.

The UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) has announced that Professor Helen Cross, an Honorary Consultant in Paediatric Neurology at GOSH, will take up the post of Director of the institute from 1 September 2022.

Structural imagine of the brain’s regions (left) and diffusion diagram of the wiring of a brain (right), which Lewis-Spitz Surgical Scientist Aswin Chari and his team analyse together to create a ’network’, as part of new epilepsy research which reveals how children with epilepsy have brains that are wired differently to children without the condition.

New research reveals brain wiring differences in children with epilepsy

13 Jul 2022, 2:30 p.m.

Children with epilepsy have brains that are wired differently from those without the condition, a new study by our researchers has found. This new epilepsy research paves the way for improved treatment, specifically how different surgery techniques can...

Sampler in a lab in the Zayed Centre for Research

Investigating the rise in hepatitis in children

25 Jul 2022, 12:15 p.m.

Due to our world-leading expertise in genomics, we've teamed up with the UK Health Security Agency (UKHSA) to understand why more children than normal are being diagnosed with liver infections (hepatitis)...

A member of GOSH staff at their computer, wearing a mask.

Our journey to build a ‘Hospital Without Walls’

4 Aug 2022, 2 p.m.

Every day, we develop innovations in care, enabling us to be one of Europe's most digitally able hospitals. Because of this strategy, we were able to use Zoom for patient video consultations just eight days after the Covid-19 pandemic began.

Dr Mary Mathias sits on a park bench while Charlie perches on the arm rest and Mum stands behind them

New trial for innovative Haemophilia treatment begins at GOSH

31 Aug 2022, 9 a.m.

Researchers at Great Ormond Street Hospital (GOSH) have begun a new clinical trial for an innovative haemophilia treatment for boys under 12.

Europe-wide group to boost access to life-saving gene therapies

22 Sep 2022, 5 p.m.

A new Europe-wide academic group has been launched today to tackle the growing economic hurdles that are preventing new life-saving gene therapies getting to the children who need them the most.

Skye stands on the GOSH roof garden smiling while her Mum, Mairi holds her younger sister Amelia smiles and sticks her tongue out.

GOSH patient donates lung tissue for vital research

3 Oct 2022, 9:30 a.m.

Following a lung transplant in 2021, Skye donated her lung tissue to the GOSH Sample Bank in the hope that one day they will help scientists find a cure for other people living with the condition.

£35 million research boost for GOSH

14 Oct 2022, 10 a.m.

The National Institute for Health and Care Research (NIHR) has announced that the Great Ormond Street Hospital (GOSH) Biomedical Research Centre (NIHR GOSH BRC) is one of 20 centres from across the country to receive 5-years of funding.

A scientist holds a sample with gloved hands

Children at GOSH first to receive CRISPR-edited universal T-cells

27 Oct 2022, 9 a.m.

Researchers at GOSH and UCL GOS ICH are the first to use CRISPR/Cas9 technology to engineer donor T-cells to try to treat seriously ill children with resistant leukaemia

Image of rod cells in the retina of the 'mini eyes'

'Mini eyes’ help researchers understand blindness in rare condition

18 Nov 2022, 11:48 a.m.

Researchers at UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have grown ‘mini eyes’ in the lab which will help researchers understand how blindness develops in the rare genetic condition Usher syndrome.

A woman in a headscarf gestures towards some micro-gardens with a group of children looking on

Engaging with our neighbours on data, research and the environment

9 Nov 2022, 10:29 a.m.

One way to engage children in data, research and our environment is through the creation of micro-gardens. The GOSH scientists involved with the festival picked this activity to teach young people about the importance of natural spaces in urban areas...

An artwork displayed above the main lab in the ZCR reads Together we can do so much

Celebrating three years of progress and breakthroughs at the ZCR

11 Nov 2022, 4:06 p.m.

We're celebrating three years of the Zayed Centre for Research. That's another year of breakthrough research, with hundreds of clinicians and researchers collaborating to help seriously ill children from across the globe.

Alyssa on ‘cell day’ - the day she received the base-edited cell therapy. May 2022.

GOSH patient receives world-first treatment for her 'incurable' T-cell leukaemia

11 Dec 2022, 8 a.m.

In May 2022, Alyssa, 13 from Leicester, became the first reported patient in the world to receive base-edited T-cells at Great Ormond Street Hospital for Children (GOSH), in collaboration with the UCL Great Ormond Street Institute of Child Health (UCL GOS

Artificial intelligence passes radiologists’ specialist exams, just about!

28 Dec 2022, 9 a.m.

Radiologists are specialist doctors that use scans to diagnose conditions, from broken bones to cancers. In the UK they must pass a specialist exam as part of their training. For the first time, researchers have shown that an artificial intelligence...

A group of children face away from the camera with their hands in the air, looking at a scientist in a white coat, in front of a presentation on a screen

NIHR GOSH BRC funding goes into ‘space’ to share brain research

18 Jan 2023, 9 a.m.

A theatre group funded by the NIHR GOSH Biomedical Research Centre has developed their successful children’s event into an interactive online film for schools and festivals

Play area within the Clinical Research Facility

UKCRF Network awarded £2.4 million in public funding

19 Jan 2023, 11:28 a.m.

UK Clinical Research Facility Network awarded £2.4 million in public funding to support the delivery of early phase research studies

A red and blue irregular shape against a black background

Research uncovers potential for new treatments for childhood autoimmune condition

23 Jan 2023, 10:21 a.m.

Research teams at GOSH and UCL GOS ICH have uncovered key inflammation pathways involved in Juvenile Dermatomyositis (JDM).

Photo of James, a GOSH patient with DMD who took part in the trial at the hospital. He is smiling.

Combining expertise for more efficient clinical trials of the future

22 Jan 2023, 8 a.m.

A group of researchers and clinical scientists have combined their expertise to develop a new way to monitor the progression of movement disorders and increase the efficiency of clinical trials.

Hannah in a white t-shirt looks down a microscope in a busy lab

Mentoring young people at the start of their careers in science and medicine

11 Feb 2023, 8 a.m.

In August 2022, the UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) opened its laboratory doors for three days to invite members of the GOSH Young Persons’ Advisory Group for research (YPAG) to shadow researcher Merry Wilkinson.

6 GOSH YPAG members stand on the steps of the UCL Great Ormond Street Institute of Child Health

How the GOSH Young Persons’ Advisory Group for research is helping to inspire the next generation of women in science

11 Feb 2023, 8 a.m.

Our GOSH Young Persons’ Advisory Group (YPAG) for research is a group of young people aged between 10 and 21 who work closely with researchers and clinicians across GOSH and the UCL GOS ICH to advise them on many aspects of their research.