Search | Great Ormond Street Hospital

Gene therapy research boosts SMA outlook

20 Dec 2021, 9 a.m.

Researchers and doctors at GOSH have long been at the forefront of developing new treatments for Spinal Muscular Atrophy (SMA) and new research this year is helping us understand how Zolgensma, a gene therapy, can help.

Are rocket scientists and brain surgeons really smarter than everyone else?

14 Dec 2021, 10:17 a.m.

A London team of surgeons, led by Surgeon Scientist Aswin Chari at GOSH, have explored whether the phrases “It’s not rocket science” or “It’s not brain surgery” are justified, in a study in the Christmas issue of The British Medical Journal.

Predicting bacteria's resistance to antibiotics

16 Dec 2021, 1 p.m.

Researchers at GOSH and UCL are the first to identify 'pre-resistance' signs in bacteria, indicators that particular bacteria are likely to become resistant to antibiotics in the future. This will allow doctors in the future to select the best treatments

A surgeon in an operating theatre, with a screen behind him.

New funding enables vital research in childhood cancer treatment

5 Jan 2022, 3:53 p.m.

Special molecules called fluorophores could ‘light up’ living cancer cells in future treatment of neuroblastoma, with new research by our GOSH doctors underway.

Amelia and Lena together outside. Amelia is in an wheelchair. They both make faces at the camera.

Pre-screening for Spinal Muscular Atrophy could change lives

7 Jan 2022, 6 a.m.

A team from Great Ormond Street Hospital (GOSH) and the UCL GOS Institute of Child Health (ICH) have shown how ‘blood spot’ testing new-borns could identify children who will go on to develop Spinal Muscular Atrophy, (SMA).

Rates of short-sightedness increasing in the UK

19 Jan 2022, 7 p.m.

New research suggests our changing environment, as well as changing gene-environment interactions, could explain increasing rates of short-sightedness over time in the UK.

First research definition for ‘Long COVID’ in children and young people

8 Feb 2022, 9 a.m.

Teams based at UCL GOS ICH, including consultants from GOSH, have agreed the first research definition of what is meant by ‘Long COVID’ (post-acute COVID-19) in children and young people.

NIHR Great Ormond Street Hospital Biomedical Research Centre Showcase

23 Feb 2022, 5:06 p.m.

This exciting virtual event provided an opportunity for our community of researchers, funders, collaborators and external stakeholders to come together to celebrate the NIHR GOSH BRC's research activities and successes from across the last three years.

New funding boost for the Great Ormond Street Hospital Clinical Research Facility

28 Feb 2022, 1 p.m.

The National Institute for Health Research (NIHR) has announced that the Great Ormond Street Hospital (GOSH) Clinical Research Facility (CRF) is one of 28 centres from across the country to receive 5-years of funding to deliver early stage clinical resear

A portrait of Poonam Palan against a dark blue background.

How we're building on our commitment to Equality, Diversity and Inclusion (EDI)

8 Mar 2022, 10 a.m.

Meet the new EDI co-ordinator for our NIHR GOSH BRC and the UCL GOS ICH

New insights into genes behind severe Covid-19 in adults and children

8 Mar 2022, 3:36 p.m.

The world’s largest study of the genetics of critical Covid-19 involving more than 57,000 people, and many of our patients at GOSH, has revealed fresh details about some of the biological mechanisms behind the severe form of the disease.

COVID-19 vaccination study opens at GOSH

10 Mar 2022, 10:20 a.m.

For the first time, patients at Great Ormond Street Hospital and Southampton Children’s Hospital who are aged 12-17 years and immunocompromised are taking part in research to work out how they respond to COVID-19 vaccination.

Understanding why leukaemia in younger children can be harder to treat

30 Mar 2022, 3:28 p.m.

New research has begun to unravel the mystery of why a particular form of leukaemia in infants has defied efforts to improve outcomes, despite significant improvements in treating older children.

An illustration of two hands, one palm facing and one showing the back of a hand. They are drawn against a blue background.

Could touchless computers be used at Great Ormond Street Hospital?

1 Apr 2022, 2:30 p.m.

A group of researchers investigate touch-free computer technologies with the Data Research, Innovation and Virtual Environments (DRIVE) unit at Great Ormond Street Hospital for Children (GOSH).

How new gene therapy can aid children with severe immune disorder

4 Apr 2022, 10 a.m.

GOSH researchers, working with international collaborators, have shown that a new gene therapy has long term benefits for children with the severe immune disorder, Wiskott-Aldrich syndrome.

Most effective breathing support for children in intensive care identified

7 Apr 2022, 7:30 p.m.

A commonly used means of delivering additional oxygen to children in intensive care is not as effective as many clinicians assume, new research involving GOSH teams has found.

New funding for autoimmune condition at GOSH

18 May 2022, 11:04 a.m.

Researchers at GOSH and University College London Great Ormond Street Institute of Child Health (UCL GOS ICH) are one of ten national teams to receive funding from a coalition of immune-related medical research charities.

An illustration showing the acronym for Young People's Advisory Group (YPAG). It reads "changing research for the better" and features some colourful images of children.

What do young people want from Artificial Intelligence in healthcare?

18 May 2022, 4 p.m.

Artificial intelligence in healthcare is a rapidly growing field. Children and teenagers often have insightful questions about AI, but are rarely involved in the development of new technologies. See how we're changing this...

People power being used to analyse eye research at GOSH

24 May 2022, 10:40 a.m.

Months of work will be completed in a few days as members of the public help to examine high-resolution images of the potentially blinding eye condition, uveitis, as part of a project working across GOSH, UCL GOS ICH and Moorfields Eye Hospital.

$A diagram highlighting the differences between fractures in adults and children - with fractures in children presenting in multiple different and less obvious ways$

Can we use artificial intelligence (AI) to better diagnose fractures?

10 Jun 2022, 3 p.m.

Dr Susan Shelmerdine, Consultant Paediatric Radiologist at Great Ormond Street Hospital (GOSH) discusses her research into using artificial intelligence (AI) to identify fractures in children.