Search | Great Ormond Street Hospital

Paediatric Ophthalmologist and Epidemiologist Professor Jugnoo Rahi appointed NIHR Senior Investigator

26 Feb 2018, 4:04 p.m.

Professor Jugnoo Rahi has been appointed as National Institute for Health Research (NIHR) Senior Investigator in the eleventh annual competition.

UK-wide consortium to transform treatment for children and young people with arthritis and uveitis

27 Mar 2018, 5 p.m.

Researchers from the UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) will lead a UK-wide effort to drive the development of new, targeted treatments for children and young people with juvenile idiopathic art

£1 million award to push forward regenerative medicine research

13 Dec 2018, 10:19 a.m.

Researchers at Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health (ICH) are to lead a new collaboration exploring how stem cells can be engineered to evade immune responses.

AI bodysuit trial launched to help treat Duchenne muscular dystrophy

1 Feb 2018, 11:57 a.m.

A new artificially intelligent bodysuit to help understand how mobility is affected in boys with Duchenne will be trialled in a collaboration between researchers at Great Ormond Street Hospital (GOSH) and Imperial College London.

BRC researchers part of collaboration to improve efficiency of gene therapy products

26 Jul 2018, 3:56 p.m.

A new collaboration aiming to develop advanced technologies for manufacturing ex vivo gene therapy products has been established between researchers at UCL Great Ormond Street Institute of Child Health (ICH) and Plasticell, a developer of stem cell techno

Meredyth Wilkinson, one of the study's first authors

Cutting edge new method reveals novel cause of Juvenile dermatomyositis

25 Jun 2018, 10:18 a.m.

A new in-depth method has helped shed light on the key role of B cells, a type of immune cell, in the rare childhood condition Juvenile dermatomyositis (JDM).

Driving forward medical device development

2 Oct 2019, 4:57 p.m.

The NIHR GOSH BRC last month hosted an inaugural medical devices workshop, in partnership with the UCL Institute of Healthcare Engineering.

Drug for Duchenne Muscular Dystrophy shows promise in clinical trial

21 Aug 2017, 12:02 p.m.

An international clinical trial has found that the drug ataluren can improve mobility for children with a severe form of Duchenne muscular dystrophy (DMD).

Film celebrates success of Biomedical Research Centres set up by outgoing UK Chief Medical Officer

14 Oct 2019, 11:37 a.m.

NHS patients who have taken part in clinical trials have expressed their gratitude to researchers in a film celebrating the work of the National Institute for Health Research (NIHR) Biomedical Research Centres (BRCs), including GOSH BRC, to mark the retir

First children have gene therapy treatment for blindness at GOSH

18 Feb 2020, 5:33 p.m.

The first paediatric patients have received a pioneering new gene therapy that can restore eyesight at Great Ormond Street Hospital.

Phoebe and Fenella took part in a clinical trial at GOSH

First drug to reduce fever flares in children with recurrent fever conditions

17 Aug 2018, 12:02 p.m.

Injections of the drug canakinumab significantly reduced the number of fever episodes in children with three different types of recurrent fever conditions, in an international trial led at GOSH by Professor Paul Brogan.

Test tubes on a revolving plate in a lab

Funding boost to develop novel therapy for rare metabolic condition

1 Apr 2019, 10:19 a.m.

GOSH and UCL Great Ormond Street Institute of Child Health (ICH) researchers Professor Paul Gissen and Dr Julien Baruteau will be part of a new collaboration with Evox Therapeutics that aims to develop a new therapy for the life threatening metabolic cond

Gene therapy treatment manufactured at GOSH and ICH used to treat world's first patient with life limiting genetic condition, MPSIIIA

28 May 2019, noon

A two-year old patient at the Royal Manchester Children’s Hospital (RMCH) is the first in the world to receive a pioneering new gene therapy treatment for the rare and life-limiting genetic condition, Mucopolysaccharidosis IIIA (MPSIIIA). The treatment wa

Trying a vegetable biopsy at the BRC Family Fun Day

Getting hands-on with research

23 Oct 2018, 2:58 p.m.

Last weekend, we opened our doors to over 300 visitors for the annual Family Fun Day hosted by the National Institute for Health Research (NIHR) Great Ormond Street Hospital (GOSH) Biomedical Research Centre (BRC).

Jude Starbeam: communicating research through theatre

31 Jul 2018, 12:30 p.m.

GOSH researchers who specialise in childhood brain injury helped shape a new play that tells the story of a little boy astronaut, Jude Starbeam, who gets lost in space.

New genetic test leads to faster, more accurate diagnosis of childhood eye disorders

11 Dec 2017, 11:21 a.m.

A new test to help diagnose and predict a range of serious childhood eye conditions has been developed by researchers at Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health (ICH).

New sequencing method can diagnose bone abnormalities in fetuses

22 Apr 2018, 5:10 p.m.

Research led by Professor Lyn Chitty has shown that prenatal exome sequencing in fetuses can provide accurate and timely molecular diagnoses for skeletal conditions and inform pregnancy management.

Ian Simcock - Research Radiographer at GOSH

NIHR Clinical Doctoral Fellowships at GOSH: Class of 2018

15 May 2018, 3:02 p.m.

Three Great Ormond Street Hospital (GOSH) staff members have been awarded National Institute for Health Research (NIHR) Clinical Doctoral Fellowships.

NIHR GOSH BRC spinout Orchard Therapeutics signs strategic agreement with GSK

13 Apr 2018, 1:10 p.m.

GSK and Orchard Therapeutics today announced a strategic agreement, under which GSK will transfer its portfolio of approved and investigational rare disease gene therapies to Orchard, securing the continued development of the programmes and access for pat

Novel therapy for Battens Disease available on the NHS

19 Sep 2019, 4:04 p.m.

Patients at Great Ormond Street Hospital (GOSH) and across England are set to receive treatment for the rare nervous system condition Battens Disease, following a deal between the NHS and manufacturer Biomarin. The drug, which is called cerliponase alfa o