Search | Great Ormond Street Hospital

Uncovering how human embryos develop in major new research project

29 Jul 2019, 10:07 a.m.

A new research project aiming to understand the earliest stages of human development is set to launch, led by scientists at the UCL Great Ormond Street Institute for Child Health (ICH).

100,000 Genomes Project hits half way mark

21 Feb 2018, 4:02 p.m.

The pioneering 100,000 Genomes Project has reached the 50,000 genomes landmark. It’s a milestone that has only been made possible through the generous participation of tens of thousands of patients and their families, including 1,492 GOSH families.

Advances in the treatment of the severe immune disorder Wiskott-Aldrich syndrome

20 Nov 2017, 2:29 p.m.

Researchers at Great Ormond Street Hospital (GOSH) have made an important breakthrough in understanding how the immune system becomes disrupted in Wiskott-Aldrich syndrome (WAS), a genetic disorder where the patient’s immune cells begin attacking their ow

GOSH researcher Karin Straathof in the lab

Dr Karin Straathof receives Sparks Early Career Investigator Award

27 Mar 2018, 2:28 p.m.

Dr Karin Straathof has been awarded the prestigious Sparks Simon Newell Early Career Investigator award in recognition of her outstanding work focused on understanding and harnessing the power of the immune system in treatment of childhood cancer.

Dr Owen Arthurs awarded NIHR Career Development Fellowship

20 Oct 2017, 3:20 p.m.

Dr Owen Arthurs has been awarded a Career Development Fellowship (CDF) from the National Institute for Health Research (NIHR).

New tablet reduces symptoms for young people with multiple sclerosis

17 Jan 2018, 12:30 p.m.

A daily tablet has been shown to reduce the debilitating symptoms experienced by children with Multiple Sclerosis (MS) and cut the chance of relapse by 82%. There are currently no treatments specifically approved for adolescents with MS and this is the fi

Paediatric Ophthalmologist and Epidemiologist Professor Jugnoo Rahi appointed NIHR Senior Investigator

26 Feb 2018, 4:04 p.m.

Professor Jugnoo Rahi has been appointed as National Institute for Health Research (NIHR) Senior Investigator in the eleventh annual competition.

UK-wide consortium to transform treatment for children and young people with arthritis and uveitis

27 Mar 2018, 5 p.m.

Researchers from the UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) will lead a UK-wide effort to drive the development of new, targeted treatments for children and young people with juvenile idiopathic art

£1 million award to push forward regenerative medicine research

13 Dec 2018, 10:19 a.m.

Researchers at Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health (ICH) are to lead a new collaboration exploring how stem cells can be engineered to evade immune responses.

AI bodysuit trial launched to help treat Duchenne muscular dystrophy

1 Feb 2018, 11:57 a.m.

A new artificially intelligent bodysuit to help understand how mobility is affected in boys with Duchenne will be trialled in a collaboration between researchers at Great Ormond Street Hospital (GOSH) and Imperial College London.

BRC researchers part of collaboration to improve efficiency of gene therapy products

26 Jul 2018, 3:56 p.m.

A new collaboration aiming to develop advanced technologies for manufacturing ex vivo gene therapy products has been established between researchers at UCL Great Ormond Street Institute of Child Health (ICH) and Plasticell, a developer of stem cell techno

Meredyth Wilkinson, one of the study's first authors

Cutting edge new method reveals novel cause of Juvenile dermatomyositis

25 Jun 2018, 10:18 a.m.

A new in-depth method has helped shed light on the key role of B cells, a type of immune cell, in the rare childhood condition Juvenile dermatomyositis (JDM).

Driving forward medical device development

2 Oct 2019, 4:57 p.m.

The NIHR GOSH BRC last month hosted an inaugural medical devices workshop, in partnership with the UCL Institute of Healthcare Engineering.

Drug for Duchenne Muscular Dystrophy shows promise in clinical trial

21 Aug 2017, 12:02 p.m.

An international clinical trial has found that the drug ataluren can improve mobility for children with a severe form of Duchenne muscular dystrophy (DMD).

Film celebrates success of Biomedical Research Centres set up by outgoing UK Chief Medical Officer

14 Oct 2019, 11:37 a.m.

NHS patients who have taken part in clinical trials have expressed their gratitude to researchers in a film celebrating the work of the National Institute for Health Research (NIHR) Biomedical Research Centres (BRCs), including GOSH BRC, to mark the retir

First children have gene therapy treatment for blindness at GOSH

18 Feb 2020, 5:33 p.m.

The first paediatric patients have received a pioneering new gene therapy that can restore eyesight at Great Ormond Street Hospital.

Phoebe and Fenella took part in a clinical trial at GOSH

First drug to reduce fever flares in children with recurrent fever conditions

17 Aug 2018, 12:02 p.m.

Injections of the drug canakinumab significantly reduced the number of fever episodes in children with three different types of recurrent fever conditions, in an international trial led at GOSH by Professor Paul Brogan.

Test tubes on a revolving plate in a lab

Funding boost to develop novel therapy for rare metabolic condition

1 Apr 2019, 10:19 a.m.

GOSH and UCL Great Ormond Street Institute of Child Health (ICH) researchers Professor Paul Gissen and Dr Julien Baruteau will be part of a new collaboration with Evox Therapeutics that aims to develop a new therapy for the life threatening metabolic cond

Gene therapy treatment manufactured at GOSH and ICH used to treat world's first patient with life limiting genetic condition, MPSIIIA

28 May 2019, noon

A two-year old patient at the Royal Manchester Children’s Hospital (RMCH) is the first in the world to receive a pioneering new gene therapy treatment for the rare and life-limiting genetic condition, Mucopolysaccharidosis IIIA (MPSIIIA). The treatment wa

Trying a vegetable biopsy at the BRC Family Fun Day

Getting hands-on with research

23 Oct 2018, 2:58 p.m.

Last weekend, we opened our doors to over 300 visitors for the annual Family Fun Day hosted by the National Institute for Health Research (NIHR) Great Ormond Street Hospital (GOSH) Biomedical Research Centre (BRC).