https://www.gosh.nhs.uk/our-research/our-research-infrastructure/nihr-great-ormond-street-hospital-brc/brc-news/research-demonstrates-clinical-and-economic-benefits-implementing-nipt-nhs-care-pathway/
Research demonstrates clinical and economic benefits of implementing NIPT into NHS care pathway
16 Sep 2016, 11:10 a.m.
The UK National Screening Committee, based on a research programme led by BRC-funded Professor Lynn Chitty, has recommended to the Government that NIPT for Down’s Syndrome be implemented into the NHS maternity care pathway and is currently awaiting ministerial decision.A prospective cohort study, led by BRC-funded Professor Lyn Chitty, was carried out at eight maternity units across the UK, to investigate the costs and benefits of implementing non-invasive prenatal testing (NIPT) for Down’s Syndrome into the NHS maternity care pathway.
Findings showed that implementation of the test for individuals with a risk greater than 1/150 significantly decreased the false positive rate with a subsequent significant decrease in invasive tests needed and procedure-related miscarriages. There was no significant effect on costs and an increase in the number of Down’s Syndrome cases detected. Furthermore, some women used NIPT for information only; therefore implementation of NIPT may not significantly affect the Down’s Syndrome live birth rate.
These findings have also been published in the BMJ.
Join us in the countdown to Rare Disease Day 2025
Rare Disease Day takes place annually on the last day of February and is a global opportunity to increase awareness and advocate for those living with rare conditions.
Could adapting our sinks help combat superbugs?
Discover how a Consultant Microbiologist at GOSH turned an innovative idea into a patented product that could revolutionise infection control in hospitals, schools, and airports – helping to stop superbugs like MRSA.
GOSH pilots AI tool to give clinicians more quality-time with patients
Patients and clinicians at GOSH have been taking part in the first NHS trial of a bespoke healthcare AI assistant, TORTUS, to help increase face-to-face time during appointments.
Studying the impact of environments on child health by linking big data
At GOSH we know that we're not caring for children if we're not caring for the environment. We spoke to Professor Pia Hardelid, who told us about a project which is helping us to understand the impacts of local environments on children’s health.