https://www.gosh.nhs.uk/our-research/our-research-infrastructure/nihr-great-ormond-street-hospital-brc/brc-news/?page=51

Biomedical Research Centre news

Less intensive chemotherapy avoids irreversible side effects in some childhood cancers

18 Dec 2015, 1:24 p.m.

Children with a kidney cancer known as Wilms’ tumour, who are at low risk of relapsing, can have their chemotherapy reduced. This finding comes from a European-wide trial that studied the drug doxorubicin.

High throughput screening identifies the genetic cause underlying a rare disease in a large nationwide cohort

18 Dec 2015, 1:20 p.m.

A collaborative study between ICH and the Turkish Pediatric Endocrinology Society has used high throughput DNA analysis to identify the genetic cause of primary adrenal insufficiency in more than 80% of affected children.

A new, genetic diagnostic service for ciliopathy disorders has been launched

18 Dec 2015, 1:18 p.m.

In a collaboration between Great Ormond Street Hospital (GOSH) North-East Thames Regional Genetics and the UCL Institute of Child Health, a new genetic diagnostic service for ciliopathy disorders has been launched for service delivery to the NHS.

Funding to develop immunotherapy for childhood sarcomas

18 Dec 2015, 1:01 p.m.

Biomedical Research Centre (BRC) supported Professor John Anderson has been awarded funding from Children with Cancer UK to investigate new immunotherapy approaches for childhood sarcomas.

World first use of gene-edited immune cells to treat ‘incurable’ leukaemia

10 Nov 2015, 2:18 p.m.

A new treatment that uses ‘molecular scissors’ to edit genes and create designer immune cells programmed to hunt out and kill drug resistant leukaemia has been used at Great Ormond Street Hospital (GOSH).