https://www.gosh.nhs.uk/our-research/our-research-infrastructure/nihr-great-ormond-street-hospital-brc/brc-news/?page=23

Biomedical Research Centre news

Scientists build whole functioning thymus from human cells

22 Dec 2020, 4:24 p.m.

Researchers from two leading national organisations have rebuilt a human thymus using human stem cells and a bioengineered scaffold thanks to support from the NIHR GOSH Biomedical Research Centre (BRC). Their work, which has been published in Nature Commu

Leukaemia trial shows promise and complexity of genome-edited cell therapies

12 Dec 2020, 5:16 p.m.

A ‘one size fits all’ immune therapy developed at the UCL Great Ormond Street Institute of Child Health (ICH) could help to clear cancerous cells in children and adults who have exhausted all other treatment options for B-cell acute lymphoblastic leukaemi

GOSH researchers join experts in warning of the detrimental impact of a no deal Brexit on rare diseases

11 Dec 2020, 4:24 p.m.

Experts have warned that a ‘no deal’ Brexit will result in the exclusion of the UK from the 24 European Reference Networks (ERNs) that were established to improve the care of patients bearing the lifelong burden of a rare disease, which require highly spe

New research finds that adult men are significantly more likely to need intensive care treatment for COVID-19

11 Dec 2020, 3:28 p.m.

Adult men have almost three times the odds of needing admission to intensive care and 40% higher odds of dying from COVID-19 than women, according to a new study led by researchers at UCL, Great Ormond Street Hospital and the University of Cape Town.

Promising early results in CAR T-cell trial for common childhood cancer

30 Nov 2020, 6 p.m.

Results from a phase I clinical trial Involving the UCL Great Ormond Street Institute of Child Health (ICH) show that CAR T-cell therapy could achieve activity against neuroblastoma tumours, opening the door to progress this approach towards further clini