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Biomedical Research Centre news

International Day of Women and Girls In Science | YPAG

International Day of Women and Girls in Science 2021

11 Feb 2021, 10:39 a.m.

Carrying out research into the best way to fight children’s illnesses has been one of our main ambitions ever since GOSH opened in 1852. We wanted to take this opportunity of International Day of Women and Girls in Science 2021 to highlight just som…

New Drug Targets for Childhood Cancer Neuroblastoma Identified

8 Feb 2021, 12:13 p.m.

The largest single cell study to date of the childhood cancer, neuroblastoma, has answered important questions about the genesis of the disease. Researchers from Great Ormond Street Hospital (GOSH), the Wellcome Sanger Institute and their collaborat…

GOSH-led metformin trial dramatically reduces seizures for people with Tuberous Sclerosis

2 Feb 2021, 4:28 p.m.

A team of researchers led by UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) has found that metformin – a drug commonly used to treat Type 2 diabetes – can successfully reduce symptoms associated with …

Ancient gene mutation found as the cause of rare hereditary condition for GOSH patient

18 Jan 2021, 5:11 p.m.

UK scientists have found that a 7,000-year-old genetic mutation is responsible for a rare form of hereditary motor neuropathy (HMN).

Scientists build whole functioning thymus from human cells

22 Dec 2020, 4:24 p.m.

Researchers from two leading national organisations have rebuilt a human thymus using human stem cells and a bioengineered scaffold thanks to support from the NIHR GOSH Biomedical Research Centre (BRC). Their work, which has been published in Nature Commu