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Landmark gene therapy study shows safety for children

Study gives more insight after long term follow up

Great Ormond Street Hospital is one of the world’s leading children’s hospitals.

Since 1852 we’ve had the privilege of working to discover better, kinder treatments for the rarest and most complex illnesses to help children reach their full potential.

GOSH in numbers

750

patients seen each day

Every day seriously ill children and young people are seen at GOSH for life-changing treatment and care

212

active clinical trials

Transformational clinical trials are currently happening throughout the hospital

18,605

learning opportunities delivered

GOSH Learning Academy provides multi-professional paediatric healthcare education and training

GOSH news

A boy stood with his mum, dad, two brothers and sisters

Landmark gene therapy study shows safety for children

16 Oct 2025, 9:54 a.m.

Results from the largest cohort of children who received a gene therapy for a rare immunodeficiency condition have shown the long-term safety and efficacy of the curative treatment.
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The words "GOSH Mental Health Framework 2025 to 2030" with a green ribbon

GOSH marks World Mental Health Day with new mental health framework

9 Oct 2025, 1 p.m.

We are proud to announce our new mental health framework - ‘Together we thrive: Building a community for mental health’.
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Amelia and Lena and their parents stand in front of the Family Wall smiling.

The Family Wall Project continues

2 Oct 2025, 2:43 p.m.

Great Ormond Street Hospital Family Wall highlights complex mix of specialist care and all the teams involved in patient journeys.
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Blue stripes are interspersed with bright green patterns in a irregular rectangular shape on a black background

New study pinpoints why some transplanted kidneys are rejected

17 Sep 2025, 8:44 p.m.

Researchers at University College London (UCL), the Wellcome Sanger Institute and the University of Cambridge combined technology that determines the genetic or RNA sequence of individual cells with powerful 3D imaging to look at lymphatic vessels
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The new Great Ormond Street Hospital Entrance on Guilford Street. A large glass covered building now decorated with floral artwork.

Great Ormond Street Hospital for Children NHS Foundation Trust (GOSH) is looking for a new Non-Executive Director to focus on finance

2 Oct 2025, 11:37 a.m.

Applications close on 17 October 2025.
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two consultant doctors sat facing each other having conversation with screens behind them

GOSH-led trial of AI-scribe technology shows ‘transformative’ benefits for patients and clinicians across London

4 Sep 2025, 6 a.m.

A major GOSH-led study has found that AI-scribing technology can significantly reduce clinician workload while improving patient care
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